Using microbubbles to measure fluid pressure noninvasively
Monodisperse Microbubbles for Noninvasive Pressure Estimation
This study is exploring a new, gentle way to check fluid pressures in the body using special tiny bubbles and sound waves, so patients can avoid needles and catheters while getting more accurate and safer monitoring during their treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11085078 on NIH RePORTER |
What this research studies
This research investigates a new method for estimating fluid pressures in the body without the need for invasive procedures like catheters or needles. It utilizes ultrasound contrast agents, which are tiny gas-filled microbubbles that respond to sound waves, to provide a noninvasive way to measure pressures in various clinical settings. By optimizing the acoustic parameters and understanding how these microbubbles behave under different conditions, the researchers aim to improve the accuracy and sensitivity of pressure measurements. This could lead to more frequent and safer monitoring of patients' fluid pressures during treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients requiring frequent monitoring of fluid pressures, such as those with cardiac conditions or tumors.
Not a fit: Patients who do not require fluid pressure monitoring or those with contraindications to ultrasound procedures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risks and costs associated with invasive pressure measurement techniques, improving patient care.
How similar studies have performed: Previous clinical trials using similar ultrasound techniques for pressure estimation have shown promising results, indicating a potential for success in this approach.
Where this research is happening
Philadelphia, United States
- Thomas Jefferson University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Eisenbrey, John — Thomas Jefferson University
- Study coordinator: Eisenbrey, John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.