Using metabolomics to understand age-related macular degeneration
Metabolomics a Novel Tool for Investigating the Pathogenesis of Age-related Macular Degeneration
This study is looking at how tiny molecules in your body might help us understand age-related macular degeneration (AMD), a common cause of vision loss in older folks, by analyzing blood and urine samples to find changes that could predict how the disease progresses.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Eye and Ear Infirmary NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10795968 on NIH RePORTER |
What this research studies
This research investigates the role of metabolomics, which is the study of small molecules in the body, in understanding age-related macular degeneration (AMD), a leading cause of blindness in older adults. By analyzing blood and urine samples from patients, the study aims to identify specific metabolic changes associated with different stages of AMD. This approach could help in discovering biomarkers that predict the progression of the disease and improve risk assessment. The research involves recruiting patients for comprehensive ophthalmological exams and sample collection to gather data on their metabolic profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who are at risk for or diagnosed with age-related macular degeneration.
Not a fit: Patients with other forms of vision impairment unrelated to age-related macular degeneration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better risk prediction and potential treatments for age-related macular degeneration.
How similar studies have performed: Previous studies have shown success in using metabolomics to identify biomarkers in other complex conditions, suggesting potential for similar breakthroughs in AMD.
Where this research is happening
Boston, United States
- Massachusetts Eye and Ear Infirmary — Boston, United States (Active)
Researchers
- Principal investigator: Husain, Deeba — Massachusetts Eye and Ear Infirmary
- Study coordinator: Husain, Deeba
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.