Using medication and lifestyle counseling to help manage weight regain after weight loss surgery
Pharmacotherapy in conjunction with lifestyle counseling for management of weight regain after bariatric surgery (PROJECT-BARI)
This study is looking at how different medications, along with support for healthy eating and living, can help people who have gained weight back after weight loss surgery, and it’s for anyone who wants to find effective ways to manage their weight and health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-10701046 on NIH RePORTER |
What this research studies
This research investigates how pharmacotherapy, combined with lifestyle counseling, can help patients who have regained weight after bariatric surgery. Participants will be randomly assigned to receive either a medication, a combination of medications, or a placebo, while also receiving ongoing diet and lifestyle support. The study aims to determine the effectiveness of these treatments in promoting weight loss and improving overall health outcomes. By employing a rigorous trial design, the research seeks to fill a significant gap in current obesity management strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have undergone bariatric surgery and are experiencing weight regain.
Not a fit: Patients who have not had bariatric surgery or those who are not experiencing weight regain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide effective treatment options for patients struggling with weight regain after bariatric surgery.
How similar studies have performed: While pharmacotherapy for weight management is a common approach, this specific combination of medications and lifestyle counseling has not been extensively tested in this context, making it a novel investigation.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Gadde, Kishore M — University of California-Irvine
- Study coordinator: Gadde, Kishore M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.