Using math and imaging to improve breast cancer treatment while reducing side effects
Mathematical modeling and molecular imaging to maximize response while minimizing toxicities from systemic therapies in preclinical models of breast cancer
['FUNDING_R01'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-10992641
This study is looking at new ways to improve breast cancer treatments by figuring out the best timing and amounts of therapy to help shrink tumors faster while reducing side effects, and it's being tested in models before it can be used for patients like you.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded) |
| Locations | 1 site (BIRMINGHAM, UNITED STATES) |
| Trial ID | NIH-10992641 on ClinicalTrials.gov |
What this research studies
This research focuses on developing mathematical models and advanced imaging techniques to optimize breast cancer therapies. By analyzing the timing, order, and dosage of treatments, the goal is to enhance tumor control while minimizing harmful side effects associated with systemic therapies. The study aims to identify personalized treatment regimens that can achieve faster tumor response without increasing chemotherapy doses. This approach is being tested in preclinical models to ensure its effectiveness before potential application in patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with advanced breast cancer who are undergoing systemic therapies.
Not a fit: Patients with early-stage breast cancer or those not receiving systemic therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective breast cancer treatments that significantly reduce side effects for patients.
How similar studies have performed: Other research has shown promise in using mathematical modeling and imaging to improve cancer treatment outcomes, indicating that this approach has potential for success.
Where this research is happening
BIRMINGHAM, UNITED STATES
- UNIVERSITY OF ALABAMA AT BIRMINGHAM — BIRMINGHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SORACE, ANNA C — UNIVERSITY OF ALABAMA AT BIRMINGHAM
- Study coordinator: SORACE, ANNA C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: advanced breast cancer, advanced stage breast cancer, anti-cancer therapy