Using magnetic nanorods to create therapeutic vesicles for heart attack treatment
Official title: Multi-functional magnetic nanorods for constructing theranostic extracellular vesicles for treating myocardial infarction
Funded at 5m Biomed, LLC · NIH-10822702 · Data updated 2026-11-12
This study is looking at a new way to help heal the heart after a heart attack by using tiny particles from stem cells, and it aims to make sure these particles get to the heart more effectively and safely with the help of special magnets.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | 5m Biomed, LLC NIH-funded |
| Lab location | 1 site (Johns Creek, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $306,433 |
| NIH project number | 1R41HL169102-01A1 |
| Project ID | NIH-10822702 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who have experienced myocardial infarction or are at risk for cardiovascular diseases.
✕Less likely to help
Patients with non-cardiovascular conditions or those who have not experienced heart-related issues may not benefit from this research.
What this research studies
This research focuses on developing a new treatment for myocardial infarction, a serious heart condition. It explores the use of stem cell-derived extracellular vesicles, which are tiny particles that can help repair heart tissue. The approach aims to enhance the delivery of these vesicles to the heart, potentially improving their effectiveness while minimizing side effects. By utilizing magnetic nanorods, the researchers hope to create a more efficient method for administering these therapeutic agents.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer treatments for patients suffering from heart attacks.
How similar studies have gone: Previous research has shown promise in using stem cell-derived extracellular vesicles for heart repair, indicating that this approach may be viable.
Where this research is happening
-
5m Biomed, LLC
Johns Creek, United States Active
Researchers
- Principal investigator: Li, Yuancheng — 5m Biomed, LLC
- Study coordinator: Li, Yuancheng
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.