Using machine learning to predict brain injuries in patients on ECMO.

Predicting ECMO NeuroLogICal Injuries using mAchiNe Learning (PELICAN)

NIH-funded research Ut Southwestern Medical Center · NIH-11116943

This study is looking at how we can use computer technology to predict brain injuries in patients on a special life-support system called ECMO, so doctors can spot risks early and make changes to help keep patients safer and healthier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUt Southwestern Medical Center NIH-funded
Lab location1 site (Dallas, United States)
Project IDNIH-11116943 on NIH RePORTER

What this research studies

This research investigates how machine learning can be utilized to predict neurological injuries in patients receiving Extracorporeal Membrane Oxygenation (ECMO), a life-support technique for critically ill individuals. By analyzing various clinical data points and their dynamic interactions, the study aims to uncover patterns that may indicate the risk of brain injury before it occurs. The goal is to identify modifiable factors that healthcare providers can monitor and adjust to improve patient outcomes. This innovative approach seeks to enhance understanding of the mechanisms behind ECMO-related brain injuries and ultimately improve care for affected patients.

Who could benefit from this research

Good fit: Ideal candidates for this research include critically ill children and adults who are receiving ECMO support.

Not a fit: Patients who are not undergoing ECMO treatment or those with pre-existing severe neurological conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better prediction and prevention of neurological injuries in patients undergoing ECMO, improving their long-term health outcomes.

How similar studies have performed: While machine learning applications in healthcare are growing, this specific approach to predicting ECMO-related brain injuries is novel and has not been extensively tested.

Where this research is happening

Dallas, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.