Using machine learning to improve cardiovascular care based on clinical trial data

Translating Personalized Inference from Randomized Clinical Trials to Real-World Cardiovascular Care

['FUNDING_R01'] · YALE UNIVERSITY · NIH-11053517

This study is looking at how we can use computer technology to help doctors create personalized treatment plans for heart patients by analyzing data from different clinical trials, so that the care you receive is more tailored to your unique needs.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorYALE UNIVERSITY (nih funded)
Locations1 site (NEW HAVEN, UNITED STATES)
Trial IDNIH-11053517 on ClinicalTrials.gov

What this research studies

This research investigates how machine learning can be applied to data from randomized clinical trials to create personalized treatment strategies for cardiovascular patients. By analyzing clinical characteristics from diverse patient populations, the study aims to develop predictive models that can better inform real-world cardiovascular care. The research will utilize participant data from multiple clinical trials and simulate treatment effects to evaluate the effectiveness of these models in various healthcare settings. Ultimately, the goal is to bridge the gap between clinical trial findings and everyday patient care.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with cardiovascular conditions, such as coronary artery disease or heart failure, who may benefit from personalized treatment approaches.

Not a fit: Patients with non-cardiovascular conditions or those who do not have access to the necessary healthcare systems may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more tailored and effective cardiovascular treatments for patients based on their individual characteristics.

How similar studies have performed: Previous research has shown promise in using machine learning for personalized medicine, indicating potential success for this novel approach in cardiovascular care.

Where this research is happening

NEW HAVEN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: atherosclerotic coronary disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.