NIH-funded research R01 grant

Using machine learning to detect cognitive impairment early in older adults

Official title: Integrating eSAGE with EHR data using machine learning for the early detection and monitoring of cognitive impairment in individuals including those underserved

Funded at Ohio State University · NIH-11077787 · Data updated 2026-11-12

This study is testing a new tool that uses health records and smart technology to help find signs of memory problems, like Alzheimer's, especially in communities that often don't get the care they need, making it easier for everyone to check their own brain health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startMay 1, 2024
Project endFebruary 28, 2029
Funding year2025
Award (this year)$738,977
NIH project number5R01AG082044-02
Project IDNIH-11077787 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals aged 65 and older, particularly those from underserved racial and ethnic backgrounds.

Less likely to help

Patients under the age of 65 or those without cognitive impairment may not benefit from this research.

What this research studies

This research aims to integrate electronic health record (EHR) data with a new tool called eSAGE to improve the early detection and monitoring of cognitive impairment, particularly in underserved populations. By employing machine learning techniques, the project seeks to identify individuals at risk for Alzheimer's disease and mild cognitive impairment more effectively. The approach focuses on creating accessible, self-administered tests that can be used without supervision, making it easier for patients to participate in their own cognitive health assessments. The research also addresses disparities in healthcare access among different racial and ethnic groups, aiming to provide equitable solutions for early diagnosis.

Why it matters

Potential benefit: If successful, this research could lead to earlier detection of cognitive impairment, allowing for timely interventions and improved management of Alzheimer's disease.

How similar studies have gone: Previous research has shown promise in using machine learning for cognitive assessment, indicating that this approach could be effective in improving early detection.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Ning, Xia — Ohio State University
  • Study coordinator: Ning, Xia

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.