NIH-funded research Sbir 1 grant

Using machine learning to design new drugs for psychiatric disorders

Official title: Machine Learning Phenotypic De Novo Drug Design

Funded at Psychogenics, INC. · NIH-10907841 · Data updated 2026-11-12

This study is working on using smart computer techniques to help create better and safer medications for mental health conditions, so patients can have more effective treatment options that really fit their needs.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionPsychogenics, INC.
NIH-funded
Lab location1 site (Paramus, UNITED STATES)
Project startAugust 15, 2023
Project endJuly 31, 2026
Funding year2024
Award (this year)$499,946
NIH project number5R43MH134716-02
Project IDNIH-10907841 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with psychiatric disorders such as autism, bipolar disorder, or anxiety.

Less likely to help

Patients with psychiatric disorders that do not respond to pharmacological treatments or those who are not diagnosed with any CNS-related conditions may not benefit from this research.

What this research studies

This research focuses on improving drug discovery for psychiatric disorders by utilizing machine learning techniques to design new compounds. It aims to address the high failure rates in developing effective treatments by creating a model that links drug structure to their effects on behavior. By leveraging a unique screening platform and a large database of compounds, the project seeks to explore new chemical spaces that have not been previously targeted. Patients may benefit from the development of more effective and safer medications tailored to their specific conditions.

Why it matters

Potential benefit: If successful, this research could lead to the development of more effective and safer drugs for psychiatric disorders.

How similar studies have gone: Other research has shown promise in using machine learning for drug discovery, indicating that this approach could lead to significant advancements in treatment options.

Where this research is happening

  • Psychogenics, INC.
    Paramus, United States
    Active

Researchers

  • Principal investigator: Brunner, Daniela — Psychogenics, INC.
  • Study coordinator: Brunner, Daniela

Related research

Other NIH-funded projects on the same topics.

  • EEG-based drug repurposing for rare CNS diseases

    A new approach uses EEG brain signatures to find existing drugs that might help people with rare nervous-system disorders.

    NIH research Psychogenics, INC. · Paramus, UNITED STATES · NIH-11536936

  • TAAR1 agonists for stopping cocaine use

    A promising drug approach is being tested to help people with cocaine use disorder reduce or stop their cocaine use.

    NIH research Psychogenics, INC. · Paramus, UNITED STATES · NIH-11283316

  • Investigating new treatments for pain management.

    This study is looking for new ways to help manage pain better, and it could lead to improved treatments for people dealing with chronic pain.

    NIH research Psychogenics, INC. · Paramus, UNITED STATES · NIH-11211245

  • Analyzing brain wave patterns to find new uses for existing drugs in rare diseases

    This study is looking to find new ways to use existing medications for rare diseases and mental health conditions by analyzing brain wave patterns from animal models, making it easier and cheaper to discover helpful treatments for people like you.

    NIH research Psychogenics, INC. · Paramus, UNITED STATES · NIH-11004734

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.