Using lungs from donors who die unexpectedly for transplantation
Transplanting Lungs from Uncontrolled Donation after Circulatory Death
['FUNDING_OTHER'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-10951591
This study is looking at a new way to help more people get lung transplants by using lungs from donors who passed away unexpectedly, and it aims to see if a special method of preserving these lungs can improve transplant success and patient survival.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10951591 on ClinicalTrials.gov |
What this research studies
This research investigates a method to increase the availability of lungs for transplant by utilizing organs from donors who have died unexpectedly, known as uncontrolled donation after circulatory death (uDCD). The approach involves a novel protocol that preserves lungs non-invasively for a short period after death, allowing for better outcomes similar to traditional brain death donations. The study aims to gather data on the effectiveness of this method and its potential to improve lung transplant rates and patient survival. Patients who receive these lungs could benefit from a greater chance of finding a suitable donor match.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with severe lung disease who are on the waiting list for a lung transplant.
Not a fit: Patients who are not in need of a lung transplant or those with conditions that contraindicate transplantation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly increase the number of available lungs for transplantation, improving survival rates for patients in need.
How similar studies have performed: Other research in Europe has successfully implemented similar approaches using uDCD lungs, showing promising outcomes.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK UNIVERSITY SCHOOL OF MEDICINE — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WALL, STEPHEN P — NEW YORK UNIVERSITY SCHOOL OF MEDICINE
- Study coordinator: WALL, STEPHEN P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.