Using lung fluid to better understand lung cancer
Official title: Liquid biopsy of the lung to profile lung cancer
Funded at Fred Hutchinson Cancer Center · NIH-10928159 · Data updated 2026-11-12
This study is looking at a gentle lung washing procedure to see if it can help doctors find important information about lung cancer more easily and safely, so they can provide better care for patients like you.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 15, 2020 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $377,741 |
| NIH project number | 5U01CA253166-06 |
| Project ID | NIH-10928159 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with lung cancer who require molecular profiling for optimal treatment.
✕Less likely to help
Patients with lung cancer who are not undergoing bronchoscopy or those with non-cancerous lung conditions may not benefit from this research.
What this research studies
This research investigates the use of bronchoalveolar lavage (BAL), a procedure that washes the lungs, to collect genomic and cellular biomarkers for lung cancer diagnosis and treatment. Traditional biopsy methods often yield insufficient tissue for accurate molecular profiling, leading to delays in care. By analyzing the fluid obtained from BAL, the study aims to improve the understanding of lung cancer biology and enhance treatment strategies. This approach could provide a safer and more effective means of gathering necessary information for managing lung cancer.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely lung cancer diagnoses, ultimately improving patient outcomes.
How similar studies have gone: Other research has shown promise in using similar approaches to enhance cancer diagnostics, indicating potential for success in this novel application.
Where this research is happening
-
Fred Hutchinson Cancer Center
Seattle, United States Active
Researchers
- Principal investigator: Nair, Viswam Siva — Fred Hutchinson Cancer Center
- Study coordinator: Nair, Viswam Siva
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.