Using low-frequency brain stimulation to improve thinking and movement in Parkinson's Disease
Theta burst subthalamic nucleus deep brain stimulation for cognitive and motor improvements in Parkinson's Disease
This study is looking at how a new type of brain stimulation called theta burst can help improve thinking and movement in people with Parkinson's Disease, and it compares this method to the usual stimulation to see which one works better for both mind and body.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10984399 on NIH RePORTER |
What this research studies
This research investigates the effects of theta burst deep brain stimulation (DBS) in the subthalamic nucleus on cognitive and motor functions in patients with Parkinson's Disease. The approach focuses on using low-frequency stimulation to enhance cognitive abilities such as executive function and memory, which are often impaired in Parkinson's patients. By comparing this method to traditional high-frequency stimulation, the study aims to determine if theta stimulation can provide better cognitive outcomes while also addressing motor symptoms. Patients will be monitored for improvements in both their cognitive and motor skills over the course of the study.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's Disease who experience cognitive decline alongside motor symptoms.
Not a fit: Patients with Parkinson's Disease who do not exhibit cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved cognitive function and quality of life for patients with Parkinson's Disease.
How similar studies have performed: There is growing evidence that low-frequency stimulation can improve cognitive functions in Parkinson's patients, suggesting potential success for this novel approach.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Lee, Darrin Jason — University of Southern California
- Study coordinator: Lee, Darrin Jason
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.