NIH-funded research NIH-funded research

Using low-dose aspirin to improve heart health after pregnancy complications

Official title: Postpartum low-dose aspirin to augment vascular recovery following a hypertensive disorder of pregnancy

Funded at Women and Infants Hospital-Rhode Island · NIH-11179697 · Data updated 2026-11-12

This study is looking at whether taking low-dose aspirin can help improve heart and blood vessel health in women who have had preeclampsia after giving birth, and it’s for those who want to know if this could be a helpful option for their recovery.

More Pregnancy research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWomen and Infants Hospital-Rhode Island
NIH-funded
Lab location1 site (Providence, United States)
Project startAugust 1, 2024
Project endJuly 31, 2027
Funding year2024
Award (this year)$167,722
NIH project number7K23HL168356-02
Project IDNIH-11179697 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women who have recently experienced preeclampsia and are in the immediate postpartum period.

Less likely to help

Patients who have not experienced preeclampsia or those who are not in the postpartum period may not benefit from this research.

What this research studies

This research investigates the use of low-dose aspirin to enhance vascular recovery in women who have experienced preeclampsia, a condition that can lead to high blood pressure and increased cardiovascular disease risk postpartum. The study will conduct a pilot trial to evaluate the feasibility of administering low-dose aspirin compared to a placebo in the immediate postpartum period. Participants will be monitored for changes in endothelial function and blood pressure over six months, aiming to establish a new approach to postpartum care for women at risk of cardiovascular issues.

Why it matters

Potential benefit: If successful, this research could lead to improved heart health and reduced cardiovascular disease risk for women who have had preeclampsia.

How similar studies have gone: While the approach of using low-dose aspirin postpartum is emerging, there is limited evidence on its effectiveness specifically for women with a history of preeclampsia, making this research a novel exploration.

Where this research is happening

  • Women and Infants Hospital-Rhode Island
    Providence, United States
    Active

Researchers

  • Principal investigator: Hauspurg, Alisse — Women and Infants Hospital-Rhode Island
  • Study coordinator: Hauspurg, Alisse

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.