Using low-dose aspirin to improve heart health after pregnancy complications

Postpartum low-dose aspirin to augment vascular recovery following a hypertensive disorder of pregnancy

NIH-funded research Women and Infants Hospital-Rhode Island · NIH-11179697

This study is looking at whether taking low-dose aspirin can help improve heart and blood vessel health in women who have had preeclampsia after giving birth, and it’s for those who want to know if this could be a helpful option for their recovery.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWomen and Infants Hospital-Rhode Island NIH-funded
Lab location1 site (Providence, United States)
Project IDNIH-11179697 on NIH RePORTER

What this research studies

This research investigates the use of low-dose aspirin to enhance vascular recovery in women who have experienced preeclampsia, a condition that can lead to high blood pressure and increased cardiovascular disease risk postpartum. The study will conduct a pilot trial to evaluate the feasibility of administering low-dose aspirin compared to a placebo in the immediate postpartum period. Participants will be monitored for changes in endothelial function and blood pressure over six months, aiming to establish a new approach to postpartum care for women at risk of cardiovascular issues.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who have recently experienced preeclampsia and are in the immediate postpartum period.

Not a fit: Patients who have not experienced preeclampsia or those who are not in the postpartum period may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved heart health and reduced cardiovascular disease risk for women who have had preeclampsia.

How similar studies have performed: While the approach of using low-dose aspirin postpartum is emerging, there is limited evidence on its effectiveness specifically for women with a history of preeclampsia, making this research a novel exploration.

Where this research is happening

Providence, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.