Using low-dose aspirin to improve health in older adults
Official title: ASPirin in Reducing Events in the Elderly - eXTension
Funded at Hennepin Healthcare Research Institute · NIH-10642911 · Data updated 2026-11-12
This study is looking at whether taking a low dose of aspirin every day can help older adults, especially those 70 and up, live healthier and longer by potentially preventing heart problems and dementia.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hennepin Healthcare Research Institute NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | July 15, 2019 |
| Project end | April 30, 2026 |
| Funding year | 2023 |
| Award (this year) | $8,032,026 |
| NIH project number | 5U19AG062682-05 |
| Project ID | NIH-10642911 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are healthy older adults aged 70 and above, particularly those interested in preventive health measures.
✕Less likely to help
Patients who are younger than 70 or those with existing health conditions that contraindicate aspirin use may not benefit from this research.
What this research studies
This research investigates whether low-dose aspirin can help prolong healthy living in older adults, particularly those aged 70 and above. It builds on previous findings from a large study that looked at the effects of aspirin on healthy lifespan and disability-free survival. The study aims to fill gaps in knowledge regarding the benefits of aspirin for preventing cardiovascular disease and dementia in the elderly population. Participants will be monitored over several years to assess the impact of daily aspirin use on their health outcomes.
Why it matters
Potential benefit: If successful, this research could provide evidence for using low-dose aspirin as a preventive measure to enhance the quality of life for older adults.
How similar studies have gone: Previous studies have shown mixed results regarding the benefits of aspirin in older populations, making this research both relevant and necessary to clarify its effects.
Where this research is happening
-
Hennepin Healthcare Research Institute
Minneapolis, United States Active
Researchers
- Principal investigator: Murray, Anne M — Hennepin Healthcare Research Institute
- Study coordinator: Murray, Anne M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.