Using long-acting injections to treat HIV in people who inject drugs

Long-Acting Injectables for Treatment of HIV among PWID (LIFT HIV)

NIH-funded research Johns Hopkins University · NIH-11081733

This study is looking at how well long-acting HIV medications work for people who inject drugs and have trouble sticking to daily pills, with the goal of finding better ways to help them manage their health in New Delhi, India.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11081733 on NIH RePORTER

What this research studies

This research investigates the effectiveness of long-acting antiretroviral therapy (LA ART) for people living with HIV who inject drugs, particularly focusing on those who struggle with adherence to traditional oral medications. The study will take place in New Delhi, India, and will involve a combination of ethnographic research, a randomized clinical trial, and modeling to assess the therapy's efficacy, safety, acceptability, and cost-effectiveness. By understanding the unique challenges faced by this population, the research aims to improve treatment outcomes and enhance viral suppression rates.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who inject drugs and are currently experiencing challenges with traditional oral antiretroviral therapy.

Not a fit: Patients who are not living with HIV or those who do not inject drugs may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve HIV treatment adherence and viral suppression rates among people who inject drugs.

How similar studies have performed: While long-acting therapies have shown promise in other populations, this specific approach for people who inject drugs in low- and middle-income countries is relatively novel and has not been extensively studied.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.