Using liquid biopsy to diagnose solitary pulmonary nodules
Liquid biopsy of solitary pulmonary nodule with extracellular vesicles
['FUNDING_R37'] · STATE UNIVERSITY OF NY,BINGHAMTON · NIH-10922776
This study is looking at a new way to help doctors figure out if small spots in the lungs, called solitary pulmonary nodules, are harmless or serious by testing blood samples for tiny particles that can give clues about these spots, making diagnosis faster and easier for patients.
Quick facts
| Phase | ['FUNDING_R37'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STATE UNIVERSITY OF NY,BINGHAMTON (nih funded) |
| Locations | 1 site (BINGHAMTON, UNITED STATES) |
| Trial ID | NIH-10922776 on ClinicalTrials.gov |
What this research studies
This research investigates the use of liquid biopsy techniques to improve the diagnosis of solitary pulmonary nodules (SPNs), which are small lung opacities that can be either benign or malignant. By analyzing extracellular vesicles (EVs) found in blood plasma, the study aims to identify specific molecular signatures that can indicate the nature of these nodules more accurately and quickly than current imaging methods. This approach seeks to reduce the time and costs associated with traditional diagnostic procedures, potentially leading to earlier and more effective treatment for patients. The research will involve collecting blood samples from patients with SPNs and analyzing the EVs for diagnostic purposes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been diagnosed with solitary pulmonary nodules and are undergoing evaluation for their nature.
Not a fit: Patients who do not have solitary pulmonary nodules or those with other unrelated lung conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to faster and more accurate diagnoses of lung nodules, allowing for timely treatment and improved patient outcomes.
How similar studies have performed: Preliminary studies have shown promise in using liquid biopsy techniques for cancer diagnosis, suggesting that this approach may be effective for solitary pulmonary nodules as well.
Where this research is happening
BINGHAMTON, UNITED STATES
- STATE UNIVERSITY OF NY,BINGHAMTON — BINGHAMTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WAN, YUAN — STATE UNIVERSITY OF NY,BINGHAMTON
- Study coordinator: WAN, YUAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers