Using liposomal azithromycin to reduce heart inflammation
Liposomal azithromycin to treat cardiac inflammation
['FUNDING_OTHER'] · UNIVERSITY OF KENTUCKY · NIH-11040627
This study is looking at a special version of the antibiotic azithromycin to see if it can help your heart heal better after a heart attack by calming down inflammation and helping your immune system work in a positive way.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF KENTUCKY (nih funded) |
| Locations | 1 site (LEXINGTON, UNITED STATES) |
| Trial ID | NIH-11040627 on ClinicalTrials.gov |
What this research studies
This research investigates the use of a special formulation of azithromycin, an antibiotic, to help reduce inflammation in the heart after events like heart attacks. The study focuses on how this treatment can change the behavior of immune cells to promote healing rather than causing further damage. By targeting the inflammatory response that follows myocardial infarctions, the research aims to improve heart recovery and prevent complications. Patients may be monitored for changes in heart function and inflammation markers during the treatment process.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a myocardial infarction or have other forms of cardiac inflammation.
Not a fit: Patients with stable coronary artery disease who have not experienced recent heart events may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a new treatment that significantly improves recovery and outcomes for patients with heart inflammation after heart attacks.
How similar studies have performed: Previous research has shown promise in using similar approaches to modulate inflammation in cardiac conditions, suggesting potential for success in this area.
Where this research is happening
LEXINGTON, UNITED STATES
- UNIVERSITY OF KENTUCKY — LEXINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VENDITTO, VINCENT JOSEPH — UNIVERSITY OF KENTUCKY
- Study coordinator: VENDITTO, VINCENT JOSEPH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: atherosclerotic coronary disease