Using light to help the brain recover from injury
Engineering neuroplasticity using volitional control of activity-dependent optogenetic stimulation in macaque sensorimotor cortex
This study is looking at ways to help the brain heal itself after injuries, like strokes, by using light to stimulate specific areas in the brain of macaques, and the findings could lead to better recovery methods for people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11006227 on NIH RePORTER |
What this research studies
This research investigates how to enhance the brain's natural ability to reorganize itself after injury, specifically focusing on the sensorimotor cortex in macaques. By using advanced techniques to control brain activity with light, the researchers aim to stimulate specific areas of the brain to promote recovery and improve function. The study will explore how this targeted stimulation can strengthen existing neural connections and create new ones, particularly in cases where there has been damage due to conditions like stroke. Patients may benefit from insights gained about how to apply these techniques in human rehabilitation.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals recovering from brain injuries, such as strokes, who may benefit from enhanced neuroplasticity.
Not a fit: Patients with non-neurological conditions or those who do not have brain injuries may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve recovery outcomes for patients with brain injuries.
How similar studies have performed: While the approach of using optogenetic stimulation is innovative, similar studies have shown promise in enhancing neuroplasticity, suggesting potential for success.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Yazdan Shahmorad, Azadeh — University of Washington
- Study coordinator: Yazdan Shahmorad, Azadeh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.