Using light to help the brain recover from injury
Engineering neuroplasticity using volitional control of activity-dependent optogenetic stimulation in macaque sensorimotor cortex
This study is exploring how using special light can help the brains of macaque monkeys heal and improve after an injury, with the hope that it could lead to better recovery methods for people with similar brain issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10890743 on NIH RePORTER |
What this research studies
This research investigates how targeted light stimulation can enhance the brain's ability to reorganize itself after injury, specifically in the sensorimotor cortex of macaque monkeys. By employing advanced engineering tools, the study aims to manipulate neural activity in a way that promotes recovery and strengthens existing neural connections. The researchers will assess the effectiveness of this approach through both behavioral observations and electrophysiological measurements, focusing on how the brain's natural connectivity can be leveraged for rehabilitation.
Who could benefit from this research
Good fit: Ideal candidates for this research would be individuals recovering from brain injuries or strokes who may benefit from enhanced neuroplasticity.
Not a fit: Patients with conditions unrelated to brain injury or those who do not have the capacity for neuroplasticity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that improve recovery outcomes for patients with brain injuries.
How similar studies have performed: Previous research has shown promise in using brain stimulation techniques to promote recovery, suggesting that this approach may yield significant advancements.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Yazdan Shahmorad, Azadeh — University of Washington
- Study coordinator: Yazdan Shahmorad, Azadeh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.