Using light to control platinum compounds for medical applications
Light-Controlled Supramolecular Platinum Complexes for Biomedical Applications
['FUNDING_R15'] · KENT STATE UNIVERSITY · NIH-10796064
This study is exploring a new way to use special light to help activate certain medicines that contain platinum, aiming to make treatments more effective and with fewer side effects for patients.
Quick facts
| Phase | ['FUNDING_R15'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | KENT STATE UNIVERSITY (nih funded) |
| Locations | 1 site (KENT, UNITED STATES) |
| Trial ID | NIH-10796064 on ClinicalTrials.gov |
What this research studies
This research investigates a novel method of using near-infrared (NIR) light to activate platinum-based compounds that can be used in medical treatments. By employing a technique called photo-uncaging, the researchers aim to control the release of bioactive substances in a precise manner, allowing for targeted therapy. The study focuses on developing new platinum complexes that can be activated by NIR light, which penetrates deeper into tissues compared to traditional UV light. This approach could enhance the effectiveness of treatments while minimizing side effects.
Who could benefit from this research
Good fit: Ideal candidates for this research would include patients with cancers that are currently treated with platinum-based chemotherapy.
Not a fit: Patients who do not have cancer or those whose cancers are not responsive to platinum-based therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and targeted cancer therapies with fewer side effects.
How similar studies have performed: While the use of light for drug activation is a growing field, this specific approach using NIR light with platinum complexes is relatively novel and has not been extensively tested.
Where this research is happening
KENT, UNITED STATES
- KENT STATE UNIVERSITY — KENT, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHENG, YAORONG — KENT STATE UNIVERSITY
- Study coordinator: ZHENG, YAORONG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.