NIH-funded research NIH-funded research

Using light therapy to relieve pain from jaw disorders

Official title: Photobiomodulation for the management of Temporomandibular disorder pain

Funded at University of Florida · NIH-10889280 · Data updated 2026-11-12

This study is looking at how a gentle light therapy called Photobiomodulation can help relieve pain for people with jaw pain from Temporomandibular Disorders (TMD), and we're inviting community members to see if they qualify to participate!

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Florida
NIH-funded
Lab location1 site (Gainesville, United States)
Project startJuly 1, 2022
Project endJune 30, 2028
Funding year2024
Award (this year)$671,820
NIH project number5UH3DE030433-03
Project IDNIH-10889280 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 18 and older who experience significant pain from Temporomandibular Disorders.

Less likely to help

Patients who are currently undergoing certain pain management therapies or have specific medical histories may not benefit from this research.

What this research studies

This research investigates the use of Photobiomodulation (PBM), a non-invasive light therapy, to manage pain associated with Temporomandibular Disorders (TMD). The study will involve a randomized clinical trial where participants will receive either the active PBM treatment or a sham treatment, allowing researchers to assess the effectiveness of this approach. Participants will be recruited from the community and will undergo a series of evaluations to determine their eligibility based on specific pain criteria. The goal is to understand how PBM affects inflammation and pain sensitivity in individuals suffering from TMD.

Why it matters

Potential benefit: If successful, this research could provide a new, effective non-pharmacological treatment option for patients suffering from TMD pain.

How similar studies have gone: Previous research has shown promising results with Photobiomodulation in treating various pain conditions, suggesting potential success for this approach in TMD.

Where this research is happening

  • University of Florida
    Gainesville, United States
    Active

Researchers

  • Principal investigator: Ribeiro-Dasilva, Margarete C — University of Florida
  • Study coordinator: Ribeiro-Dasilva, Margarete C

Related research

Other NIH-funded projects on the same topics.

  • Photobiomodulation for jaw pain from TMD

    A clinician-scientist at the University of Florida is testing a light-based therapy to help adults with temporomandibular disorder pain feel better and jaw function improve.

    NIH research University of Florida · Gainesville, United States · NIH-11635590

  • Targeted light therapy for jaw pain (TMD)

    This project uses targeted light therapy to try to reduce jaw pain in adults with temporomandibular disorder.

    NIH research University of Florida · Gainesville, United States · NIH-11382371

  • Female-specific trigeminal dynorphin role in TMD and migraine overlap

    This grant studies why women with jaw pain (TMD) often have migraines and looks for female-focused targets to treat both conditions.

    NIH research Texas A&m University Health Science Ctr · College Station, United States · NIH-11380671

  • Photobiomodulation for jaw pain from TMD

    A study tests a light-based therapy to help adults with temporomandibular disorder reduce jaw pain without drugs.

    NIH research University of Florida · Gainesville, United States · NIH-11361586

  • Light Therapy for Jaw Pain

    This project is exploring if a special type of light therapy, called photobiomodulation, can help adults who experience chronic pain from temporomandibular disorder (TMD).

    NIH research University of Florida · Gainesville, United States · NIH-11144545

  • Understanding jaw pain and migraine in women

    This project looks for new ways to treat jaw pain (TMD) and migraine headaches, especially in women.

    NIH research Texas A&m University Health Science Ctr · College Station, United States · NIH-11143871

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.