Using light therapy to improve brain function in older adults at risk for Alzheimer's disease

Revitalizing Cognition in Older Adults at Risk for Alzheimer's Disease with Near-Infrared Photobiomodulation

['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-10624816

This study is testing a new, gentle light therapy that shines near-infrared light through the skin and nose to help boost brain function in older adults who may be at risk for Alzheimer's disease, and it aims to see if this safe and affordable treatment can really make a difference.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF FLORIDA (nih funded)
Locations1 site (GAINESVILLE, UNITED STATES)
Trial IDNIH-10624816 on ClinicalTrials.gov

What this research studies

This research investigates a new treatment that uses near-infrared light to enhance cognitive function in older adults who are at risk for Alzheimer's disease. The approach involves delivering light through the skin and nose to stimulate brain activity and improve energy production in brain cells. By collaborating with teams from the University of Florida and the University of Arizona, the study aims to assess the effectiveness of this low-cost and low-risk therapy. Previous studies have shown promising results in animal models and preliminary human trials, suggesting that this method could help protect against cognitive decline.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults who are cognitively normal but at increased risk for developing Alzheimer's disease.

Not a fit: Patients who are already diagnosed with advanced Alzheimer's disease or other severe cognitive impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a new, non-invasive treatment option that improves cognitive function and quality of life for older adults at risk for Alzheimer's disease.

How similar studies have performed: Previous studies have shown promising results with similar light therapy approaches in both animal models and preliminary human trials, indicating potential for success.

Where this research is happening

GAINESVILLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.