Using light therapy to improve blood flow in the brains of Alzheimer's patients

Using Photobiomodulation to Alleviate Brain Hypoperfusion in Alzheimer's Disease

NIH-funded research University of Texas Hlth Sci Ctr Houston · NIH-11077849

This study is looking at how light therapy might help improve blood flow in the brains of people with Alzheimer's by targeting a specific protein, with the hope that this could boost brain function and memory.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Sci Ctr Houston NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11077849 on NIH RePORTER

What this research studies

This research investigates how light therapy, specifically photobiomodulation, can improve blood flow in the brains of individuals with Alzheimer's disease. The study focuses on a specific protein that may play a role in brain health and aims to understand how inhibiting this protein can enhance blood circulation and cognitive function. By using a non-invasive light treatment, the researchers hope to restore normal brain function and reduce memory deficits associated with Alzheimer's. The research will be conducted using a mouse model that mimics Alzheimer's disease to gather insights that could eventually benefit human patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias, particularly those experiencing cognitive impairments.

Not a fit: Patients with early-stage Alzheimer's or those without significant cognitive deficits may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new non-invasive treatments that improve cognitive function and quality of life for Alzheimer's patients.

How similar studies have performed: Previous research has shown promising results using similar light therapy approaches in other neurological conditions, indicating potential for success in this area.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.