Using light therapy to enhance exercise for better mobility in older adults with peripheral artery disease.

ENhancing exercise with LIGHT to improve functioning in PAD: the ENLIGHTEN PAD Trial

NIH-funded research Northwestern University at Chicago · NIH-10851012

This study is looking at whether using special red light therapy before walking exercises can help older adults with peripheral artery disease walk longer and feel better, making it easier for them to stay active at home.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10851012 on NIH RePORTER

What this research studies

This research investigates the use of 670 nm light therapy to improve the effectiveness of walking exercises for older adults suffering from peripheral artery disease (PAD). The study aims to determine if administering light therapy before exercise can help increase the duration and intensity of walking, thereby enhancing overall mobility and reducing symptoms. Participants will engage in home-based walking exercises, with some receiving light therapy to see if it improves their exercise adherence and outcomes. The approach focuses on leveraging the body's natural signaling mechanisms to improve blood flow and muscle function.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults diagnosed with peripheral artery disease who experience walking difficulties.

Not a fit: Patients who do not have peripheral artery disease or those who are unable to participate in walking exercises may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve mobility and quality of life for patients with peripheral artery disease.

How similar studies have performed: Previous studies have shown promising results with light therapy in enhancing exercise outcomes, suggesting potential for success in this approach.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.