Using leg heat therapy to help people with peripheral artery disease improve their physical performance
Official title: Leg heat therapy to improve functional performance in peripheral artery disease
Funded at Purdue University · NIH-11083011 · Data updated 2026-11-12
This study is looking at how wearing special heated trousers at home can help people with peripheral artery disease (PAD) feel better and move more easily by improving blood flow and muscle strength.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Purdue University NIH-funded |
| Lab location | 1 site (West Lafayette, United States) |
| Project start | May 15, 2022 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $431,752 |
| NIH project number | 5R01AG073634-04 |
| Project ID | NIH-11083011 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with lower-extremity peripheral artery disease who experience limitations in physical functioning.
✕Less likely to help
Patients with severe cardiovascular conditions or those unable to use the leg heat therapy system may not benefit from this research.
What this research studies
This research investigates the effects of home-based leg heat therapy on individuals suffering from peripheral artery disease (PAD), a condition that significantly impacts mobility and quality of life. The therapy involves wearing specially designed trousers that circulate warm water to heat the legs, which aims to enhance muscle strength and improve blood flow. Participants will use this system in the comfort of their own homes, making it a convenient and non-invasive option for improving their physical functioning. The study builds on previous findings that suggest heat therapy can aid recovery and enhance muscle performance.
Why it matters
Potential benefit: If successful, this research could lead to improved mobility and quality of life for patients with peripheral artery disease.
How similar studies have gone: Previous studies have shown promising results with similar heat therapy approaches, indicating potential for success in this novel application.
Where this research is happening
-
Purdue University
West Lafayette, United States Active
Researchers
- Principal investigator: Roseguini, Bruno T — Purdue University
- Study coordinator: Roseguini, Bruno T
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Low-dose colchicine for reducing vascular risk in people with PAD
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.