Using leg heat therapy to help people with peripheral artery disease improve their physical performance

Leg heat therapy to improve functional performance in peripheral artery disease

NIH-funded research Purdue University · NIH-11083011

This study is looking at how wearing special heated trousers at home can help people with peripheral artery disease (PAD) feel better and move more easily by improving blood flow and muscle strength.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPurdue University NIH-funded
Lab location1 site (West Lafayette, United States)
Project IDNIH-11083011 on NIH RePORTER

What this research studies

This research investigates the effects of home-based leg heat therapy on individuals suffering from peripheral artery disease (PAD), a condition that significantly impacts mobility and quality of life. The therapy involves wearing specially designed trousers that circulate warm water to heat the legs, which aims to enhance muscle strength and improve blood flow. Participants will use this system in the comfort of their own homes, making it a convenient and non-invasive option for improving their physical functioning. The study builds on previous findings that suggest heat therapy can aid recovery and enhance muscle performance.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with lower-extremity peripheral artery disease who experience limitations in physical functioning.

Not a fit: Patients with severe cardiovascular conditions or those unable to use the leg heat therapy system may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved mobility and quality of life for patients with peripheral artery disease.

How similar studies have performed: Previous studies have shown promising results with similar heat therapy approaches, indicating potential for success in this novel application.

Where this research is happening

West Lafayette, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.