Using laser particles to analyze individual cells in real time
Laser particles for multi-dimensional single-cell analysis
This study is exploring new ways to use lasers to look closely at individual cells, helping scientists see how they work and change over time, which could lead to better treatments for diseases.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10889088 on NIH RePORTER |
What this research studies
This research aims to enhance our understanding of cells by developing innovative laser particle technologies that allow for multi-dimensional analysis of single cells. By utilizing optical barcodes, the project seeks to capture dynamic cellular processes in real time, enabling researchers to observe how cells interact and change over time. The approach combines laser particles with oligonucleotide barcodes to gather extensive data on cellular functions and behaviors in vivo. This could lead to significant advancements in the field of life sciences and improve our understanding of various diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that involve complex cellular interactions, such as cancer or autoimmune diseases.
Not a fit: Patients with stable, non-dynamic conditions that do not involve significant cellular changes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide deeper insights into cellular behavior and interactions, potentially leading to improved diagnostics and treatments for various diseases.
How similar studies have performed: Other research has shown promise in using advanced single-cell analysis techniques, but this specific approach with laser particles is relatively novel.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Yun, Seok-Hyun Andy — Massachusetts General Hospital
- Study coordinator: Yun, Seok-Hyun Andy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.