Using language analysis to understand disorganized speech in psychosis
Advancing Computational Linguistic Biomarkers of Disorganized Speech in Psychosis
This study is looking at how to better understand and measure disorganized speech in people with psychosis, like schizophrenia and mood disorders, by using advanced computer techniques to analyze their speech, which could help doctors predict how well treatments are working and the risk of relapse.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project ID | NIH-10911859 on NIH RePORTER |
What this research studies
This research investigates how disorganized speech in individuals with psychosis can be measured using advanced computational linguistics techniques. By analyzing speech samples from 270 participants with schizophrenia and mood disorders, the study aims to identify patterns of disorganization that may indicate treatment response and relapse risk. The researchers will develop deep-learning methods to classify speech disorganization and predict participant characteristics based on linguistic features. This approach seeks to provide a more objective and reproducible way to assess cognitive disturbances in psychosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with schizophrenia spectrum disorders or mood disorders with psychotic features.
Not a fit: Patients without any psychotic features or those not diagnosed with schizophrenia or mood disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for individuals experiencing disorganized speech in psychosis.
How similar studies have performed: Other research has shown promise in using computational linguistics for analyzing speech patterns, suggesting that this approach could yield valuable insights.
Where this research is happening
Manhasset, United States
- Feinstein Institute for Medical Research — Manhasset, United States (Active)
Researchers
- Principal investigator: Tang, Sunny Xiaojing — Feinstein Institute for Medical Research
- Study coordinator: Tang, Sunny Xiaojing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.