Using ketamine to help mothers with depression and pain after cesarean delivery

Ketamine to reduce postpartum depression and pain after cesarean delivery

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-11086759

This study is looking at how ketamine can help new moms feel better by reducing postpartum depression and pain after a cesarean delivery, and it aims to find the best dose to improve their mood and manage pain safely.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-11086759 on NIH RePORTER

What this research studies

This research investigates the use of ketamine to alleviate postpartum depression and pain in mothers who have undergone cesarean delivery. The study aims to determine the optimal dosage of ketamine and its effects on pain management and mood improvement in this specific population. By focusing on the unique challenges faced by new mothers, the research seeks to provide a more effective treatment option that considers both pain relief and mental health. Participants will be monitored for side effects and overall recovery to ensure the safety and efficacy of the treatment.

Who could benefit from this research

Good fit: Ideal candidates for this research are mothers who have recently undergone a cesarean delivery and are experiencing symptoms of postpartum depression or pain.

Not a fit: Patients who have not had a cesarean delivery or those who do not experience postpartum depression or pain may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new treatment option that significantly reduces postpartum depression and pain for mothers after cesarean delivery.

How similar studies have performed: While there have been limited studies on ketamine for postpartum conditions, this research aims to fill a significant knowledge gap and explore its effects specifically in postpartum women after cesarean delivery.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.