NIH-funded research NIH-funded research

Using iron and copper to create new methods for nitrogen fixation and organic synthesis

Official title: Catalytic Nitrogen Fixation and C-N Bond Constructions Mediated by Iron and Copper as Models of Biocatalysis and Tools for Organic Synthesis

Funded at California Institute of Technology · NIH-11070346 · Data updated 2026-11-12

This study is looking at new ways to help plants and make medicines by using special metals like iron and copper to create important chemical bonds, which could lead to better farming and drug development for everyone.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionCalifornia Institute of Technology
NIH-funded
Lab location1 site (Pasadena, United States)
Project startMay 1, 2024
Project endApril 30, 2029
Funding year2025
Award (this year)$410,249
NIH project number5R35GM153322-02
Project IDNIH-11070346 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research include individuals interested in advancements in drug development or agricultural technologies.

Less likely to help

Patients with conditions unrelated to drug synthesis or agricultural applications may not receive direct benefits from this research.

What this research studies

This research focuses on developing innovative methods for nitrogen fixation and constructing carbon-nitrogen bonds using iron and copper as catalysts. By studying the mechanisms of these reactions, the research aims to create more efficient biocatalytic processes that mimic natural enzymes. Patients may benefit from advancements in drug synthesis and agricultural applications that arise from these new chemical methods. The research employs a combination of electrochemical and photochemical techniques to explore and optimize these catalytic processes.

Why it matters

Potential benefit: If successful, this research could lead to more efficient production of essential compounds used in pharmaceuticals and agriculture.

How similar studies have gone: Previous research has shown promising results in using similar catalytic approaches for nitrogen fixation and organic synthesis.

Where this research is happening

  • California Institute of Technology
    Pasadena, United States
    Active

Researchers

  • Principal investigator: Peters, Jonas C — California Institute of Technology
  • Study coordinator: Peters, Jonas C

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.