Using intrathecal baclofen to treat dystonia in children with cerebral palsy.
Intrathecal baclofen and pediatric dystonia.
This study is looking at how a special treatment called intrathecal baclofen can help kids with cerebral palsy who have muscle control issues, aiming to see if it can make their movements easier and improve their daily lives over a year.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10882869 on NIH RePORTER |
What this research studies
This research investigates the use of intrathecal baclofen (ITB) to manage dystonia in children diagnosed with cerebral palsy. The study aims to understand how ITB can improve muscle control, mobility, and overall quality of life for these children. By using a standardized protocol to adjust the dosage of ITB, researchers will observe its effects over a 12-month period, focusing on children with varying levels of dystonia, spasticity, and pain. The goal is to provide clearer insights into the benefits and limitations of ITB treatment for this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have been diagnosed with cerebral palsy and experience dystonia.
Not a fit: Patients who do not have cerebral palsy or those whose dystonia is not related to brain injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management of dystonia in children, enhancing their mobility and quality of life.
How similar studies have performed: Previous studies have shown some success with intrathecal baclofen in managing symptoms of dystonia, although this specific approach is designed to address limitations found in earlier research.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Thomas, Sruthi Pandipati — Baylor College of Medicine
- Study coordinator: Thomas, Sruthi Pandipati
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.