NIH-funded research Sbir 2 grant

Using interactive gaming to help prevent cognitive decline in Parkinson's disease.

Official title: Neuro-exergaming for the Prevention and Remediation of Decline due to Parkinson's Disease: Clinical Trial of the Interactive Physical and Cognitive Exercise System (iPACES v3)

Funded at Ipaces, LLC · NIH-10906190 · Data updated 2026-11-12

This study is looking at whether a fun exercise program that mixes physical activity with brain games can help people with Parkinson's disease keep their thinking skills sharp and lower their chances of getting dementia.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionIpaces, LLC
NIH-funded
Lab location1 site (Clifton Park, United States)
Project startAugust 11, 2023
Project endJuly 31, 2026
Funding year2024
Award (this year)$1,381,504
NIH project number5R44NS132690-02
Project IDNIH-10906190 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with Parkinson's disease, particularly those experiencing early signs of cognitive decline.

Less likely to help

Patients with advanced Parkinson's disease or those who are unable to participate in physical activities may not benefit from this research.

What this research studies

This research investigates the use of an interactive physical and cognitive exercise system, known as iPACES v3, to help individuals with Parkinson's disease maintain their cognitive abilities. Participants will engage in exergaming, which combines physical exercise with cognitive challenges, to see if this approach can slow down cognitive decline and reduce the risk of developing dementia. The study will involve a randomized controlled trial to assess the effectiveness of this intervention over a period of time.

Why it matters

Potential benefit: If successful, this research could provide a novel non-pharmacological intervention to help preserve cognitive function in patients with Parkinson's disease.

How similar studies have gone: Previous studies have shown promising results with exergaming as a cognitive intervention for older adults, indicating potential for success in this novel application.

Where this research is happening

  • Ipaces, LLC
    Clifton Park, United States
    Active

Researchers

  • Principal investigator: Gillen, Robert Willson — Ipaces, LLC
  • Study coordinator: Gillen, Robert Willson

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.