Using immune therapies to treat complex regional pain syndrome
Immune modulating therapies to treat complex regional pain syndrome
This study is looking at how treatments that adjust the immune system might help people with complex regional pain syndrome (CRPS) by understanding how the immune system affects their pain, with the goal of finding better ways to relieve their symptoms and improve their daily lives.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Drexel University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10583271 on NIH RePORTER |
What this research studies
This research investigates how immune modulating therapies can help treat complex regional pain syndrome (CRPS), a chronic pain condition that affects the limbs. The study focuses on understanding the immune system's role in CRPS, particularly how certain T cells and inflammatory signals contribute to pain hypersensitivity. By exploring the mechanisms behind immune dysregulation in CRPS, the research aims to develop targeted therapies that could alleviate symptoms and improve patients' quality of life.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with complex regional pain syndrome who experience chronic pain in one or more extremities.
Not a fit: Patients with pain conditions unrelated to immune dysregulation or those who do not have a diagnosis of complex regional pain syndrome may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly reduce pain and improve function for patients with complex regional pain syndrome.
How similar studies have performed: Previous research has shown promise in using immune modulation to treat chronic pain conditions, suggesting that this approach could be effective for CRPS as well.
Where this research is happening
Philadelphia, United States
- Drexel University — Philadelphia, United States (Active)
Researchers
- Principal investigator: Ajit, Seena — Drexel University
- Study coordinator: Ajit, Seena
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.