Using imaging to understand the tumor environment in early prostate cancer
Translational imaging biomarkers of the tumor microenvironment in early prostate cancer
This study is looking at how the genes and cells in prostate cancer tumors relate to special imaging tests, like MRI and PET scans, to help find and treat the cancer earlier and more effectively for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10918241 on NIH RePORTER |
What this research studies
This research aims to connect the genetic and cellular characteristics of the tumor microenvironment in prostate cancer with imaging biomarkers that can help detect and treat the disease early. Patients with primary prostate cancer will undergo advanced imaging techniques, including multi-parametric magnetic resonance imaging (mpMRI) and PET/CT scans, to identify specific cellular interactions within the tumor environment. By analyzing these imaging results alongside pathology data, the research seeks to uncover how different tumor regions behave and respond to treatment, potentially leading to more personalized and effective interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with intermediate to high-risk primary prostate cancer.
Not a fit: Patients with low-risk prostate cancer or those who have already undergone treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and more targeted treatment options for patients with prostate cancer.
How similar studies have performed: Previous research has shown promise in using imaging biomarkers to understand tumor environments, suggesting that this approach could yield valuable insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Pomper, Martin G — Johns Hopkins University
- Study coordinator: Pomper, Martin G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.