Using imaging to understand how the immune system fights tumors
Non-invasive imaging of the anti-tumor immune response
['FUNDING_R01'] · BOSTON CHILDREN'S HOSPITAL · NIH-10979158
This study is exploring a new way to use special imaging technology to see how well your immune system is responding to cancer treatments, especially immunotherapy, so that doctors can better understand who is benefiting from the treatment and who might need a different approach.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON CHILDREN'S HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10979158 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced imaging techniques to monitor the immune response to cancer treatments, specifically immunotherapy using checkpoint blockade. By utilizing a novel imaging method called immuno-PET, the researchers aim to visualize and differentiate between patients who respond well to treatment and those who do not. The study involves tracking specific immune cells within the tumor microenvironment, allowing for early identification of treatment effectiveness. This approach could lead to more personalized cancer therapies based on individual patient responses.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients undergoing immunotherapy for cancer who are willing to participate in advanced imaging assessments.
Not a fit: Patients who are not receiving immunotherapy or those with non-cancerous conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enable more effective and tailored cancer treatments by identifying which patients are likely to benefit from specific immunotherapies.
How similar studies have performed: Other research has shown promising results using similar imaging techniques to monitor immune responses in cancer treatment, indicating a potential for success in this approach.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON CHILDREN'S HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PISHESHA, NOVALIA — BOSTON CHILDREN'S HOSPITAL
- Study coordinator: PISHESHA, NOVALIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: anti-cancer therapy