Using imaging to improve lung cancer diagnosis

Macro-vasculature: A Novel Image Biomarker of Lung Cance

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-10770368

This study is working on a new way to look at lung nodules from CT scans to help tell the difference between harmless and cancerous ones, so patients can avoid unnecessary worry and extra tests.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-10770368 on NIH RePORTER

What this research studies

This research focuses on developing a new imaging biomarker that can help distinguish between benign and malignant lung nodules detected during screening. By utilizing advanced imaging techniques, the study aims to reduce the number of false-positive results that often lead to unnecessary follow-up procedures and anxiety for patients. The researchers will validate this new biomarker across various CT scan protocols and integrate it with clinical data to enhance diagnostic accuracy. This approach seeks to improve early detection of lung cancer, ultimately aiming to save lives.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have been identified with indeterminate lung nodules during screening or those at high risk for lung cancer.

Not a fit: Patients who do not have lung nodules or are not at risk for lung cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate lung cancer screenings, reducing unnecessary procedures and improving early diagnosis.

How similar studies have performed: Previous research has shown promise in using imaging biomarkers for cancer diagnosis, indicating that this approach could be effective.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancer
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.