Using imaging techniques to monitor cancer therapy effectiveness

Metabolic Imaging of Targeted Therapies in Cancer

NIH-funded research University of Pennsylvania · NIH-11025899

This study is looking at new ways to see how well certain cancer treatments are working by checking changes in cancer cells, which could help doctors understand faster if the treatment is effective for patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-11025899 on NIH RePORTER

What this research studies

This research focuses on developing advanced imaging methods to evaluate how well targeted cancer therapies, particularly small-molecule kinase inhibitors, are working in patients. By analyzing gene expression and metabolic changes in cancer cells, the study aims to identify specific biomarkers that indicate treatment response. The approach includes both laboratory experiments and non-invasive imaging techniques to track metabolic alterations in tumors over time. This could provide a more timely and accurate assessment of therapy effectiveness compared to traditional methods.

Who could benefit from this research

Good fit: Ideal candidates for this research are cancer patients undergoing targeted therapy who are interested in understanding their treatment response better.

Not a fit: Patients not receiving targeted therapies or those with non-cancerous conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved monitoring of cancer treatments, allowing for more personalized and effective patient care.

How similar studies have performed: Previous research has shown promise in using imaging techniques to monitor cancer therapies, suggesting that this approach could yield valuable insights.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions anti-cancer therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.