Using imaging and RNA analysis to predict cancer recurrence in the head and neck

Who could benefit from this research

What this research studies

This research focuses on head and neck squamous cell carcinomas (HNSCCs), which are aggressive tumors that often recur after treatment. The study aims to develop methods for early prediction of cancer recurrence by combining advanced imaging techniques, such as PET and MRI, with RNA analysis to identify biomarkers associated with tumor behavior. By monitoring these biomarkers, the research seeks to improve personalized treatment strategies and enhance patient care. Patients will be evaluated through non-invasive imaging and RNA assessments to better understand their risk of recurrence.

Why it matters

Where this research is happening

• Washington University
  Saint Louis, United States Active

Researchers

• Principal investigator: Li, Hua — Washington University
• Study coordinator: Li, Hua

Related research

Other NIH-funded projects on the same topics.

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• Enhanced detection of head and neck cancer recurrence using automated EV isolation and vibrational spectroscopy

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• A saliva test to detect head and neck cancer recurrence

  This study is working on a simple saliva test called HNKlear that can help catch the return of head and neck cancer early, making it easier for patients to get the care they need without invasive procedures.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-10932401

• Keloid recurrence study using multi-omics in diverse patients

  A research effort will look at why keloids come back after surgery, especially in African American patients, using comprehensive molecular data from patient samples.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11641647

• Oral cancer recurrence predictor using tumor microbes and gene activity

  This NIH grant explores how bacteria and immune signals inside oral cancer tumors relate to whether the cancer comes back, with the aim of making a practical risk predictor for patients.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11591548

• Biomarker to guide treatment in head and neck cancer

  A biomarker test using tumor samples is being developed to predict recurrence risk in oral cancers and help tailor treatment.

  NIH research Boston University (Charles River Campus) · Boston, United States · NIH-11580855

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.