Using image-guided techniques to deliver stem cells for brain repair after injury
Official title: Image-guided intra-arterial delivery of stem cells to repair brain damage after TBI
Funded at Baltimore VA Medical Center · NIH-10951521 · Data updated 2026-11-12
This study is exploring a new way to send stem cells directly to the brain to help heal injuries from traumatic brain injury (TBI), aiming to improve recovery and reduce long-term problems for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baltimore VA Medical Center NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | October 1, 2023 |
| Project end | September 30, 2027 |
| Funding year | 2025 |
| NIH project number | 5I01BX005768-02 |
| Project ID | NIH-10951521 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced a traumatic brain injury and are seeking new treatment options.
✕Less likely to help
Patients with chronic neurological conditions unrelated to traumatic brain injury may not benefit from this research.
What this research studies
This research focuses on developing a method to deliver stem cells directly to the brain to repair damage caused by traumatic brain injury (TBI). By using image-guided intra-arterial delivery, the researchers aim to enhance the effectiveness of stem cell therapy, which has shown promise in preliminary studies. The approach seeks to overcome barriers that typically hinder effective treatment, such as the blood-brain barrier, and to address the complex inflammatory responses that occur after TBI. Patients may benefit from this innovative treatment strategy, which could lead to improved recovery and reduced long-term neurological deficits.
Why it matters
Potential benefit: If successful, this research could provide a new therapeutic option for patients suffering from the effects of traumatic brain injury.
How similar studies have gone: While the approach of using stem cells for brain repair is being explored, this specific method of image-guided intra-arterial delivery is relatively novel and has not been extensively tested in clinical settings.
Where this research is happening
-
Baltimore VA Medical Center
Baltimore, United States Active
Researchers
- Principal investigator: Walczak, Piotr — Baltimore VA Medical Center
- Study coordinator: Walczak, Piotr
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.