Using HIV genetics to target prevention in Miami‑Dade
Miami Dade County ASsessment of Phylogenetics to Improve Resource Equity: MD ASPIRE
Using HIV genetic information and local health data to find where new infections are happening fastest so prevention and care can be focused where they help most.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11308653 on NIH RePORTER |
What this research studies
This project will use HIV genetic (molecular) data collected by the county health department to spot groups and neighborhoods where the virus is spreading most quickly. Researchers will combine those findings with local program and economic data to model the best ways to direct prevention and treatment resources. All personal information will be de-identified and coded before researchers analyze it. The team will work with Miami‑Dade public health partners to turn the results into practical recommendations aimed at lowering new infections and improving viral suppression.
Who could benefit from this research
Good fit: People living with or newly diagnosed with HIV whose information is recorded in Miami‑Dade County public health surveillance databases would be the focus of the analyses.
Not a fit: People who live outside Miami‑Dade, whose data are not captured in local surveillance, or who need immediate individual clinical care rather than program-level changes may not directly benefit.
Why it matters
Potential benefit: If successful, this work could help public health programs focus prevention and treatment where they will prevent the most new HIV infections.
How similar studies have performed: Molecular cluster detection has helped find transmission hotspots before, but prior efforts rarely showed reductions in new infections, so combining phylodynamics with economic resource-allocation modeling is a relatively new approach.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Little, Susan Janet — University of California, San Diego
- Study coordinator: Little, Susan Janet
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.