Using high-intensity interval training to improve heart health in breast cancer survivors after chemotherapy

High Intensity Interval Training: Optimizing Exercise Therapy to Mitigate Cardiovascular Disease Risk Following Breast Cancer Chemotherapy

NIH-funded research University of Florida · NIH-10848354

This study is looking at how high-intensity interval training (HIIT) can help breast cancer survivors over 65 improve their heart health after chemotherapy, using special exercises that are easier on their balance, and it will compare this approach to regular moderate exercise to find the best way to keep them fit and healthy.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-10848354 on NIH RePORTER

What this research studies

This research investigates how high-intensity interval training (HIIT) can help breast cancer survivors, particularly those over 65, reduce their risk of cardiovascular disease after undergoing chemotherapy. The study aims to optimize exercise therapy by using a non-weight-bearing exercise ergometer, which addresses balance issues that many older survivors face. By comparing HIIT to traditional moderate-intensity continuous training, the research seeks to determine the most effective exercise regimen for improving heart health and overall physical function in this population. Participants will engage in tailored exercise sessions designed to enhance their cardiovascular fitness while considering their unique health challenges.

Who could benefit from this research

Good fit: Ideal candidates for this research are breast cancer survivors aged 65 and older who have completed chemotherapy and are experiencing cardiovascular risks or related health issues.

Not a fit: Patients who are not breast cancer survivors or those who have not undergone chemotherapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved cardiovascular health and quality of life for breast cancer survivors who have undergone chemotherapy.

How similar studies have performed: Previous research has shown that high-intensity interval training can be effective in improving cardiovascular health in various clinical populations, suggesting potential success for this approach in breast cancer survivors.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions equilibrium disordercardiovascular disorder preventioncardiac disease preventioncardiovascular disease prevention
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.