Using hemp-derived cannabidiol to help people reduce cannabis use disorder
Hemp-derived Cannabidiol for the treatment of cannabis use disorder in concentrate users: A double-blind placebo-controlled randomized trial
This study is looking at whether CBD, a compound from hemp, can help people who are struggling with cannabis use, especially those using strong cannabis products, by comparing two types of CBD—one with a little THC and one without—to see if they can ease withdrawal symptoms and reduce overall cannabis use.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado NIH-funded |
| Lab location | 1 site (Boulder, UNITED STATES) |
| Project ID | NIH-11089903 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of hemp-derived cannabidiol (CBD) in treating cannabis use disorder, particularly among users of high-potency cannabis concentrates. The study will compare the effects of two forms of CBD—one with a small amount of THC and one without—on withdrawal symptoms and overall cannabis use. Participants will be randomly assigned to receive either CBD or a placebo, and their progress will be monitored over the course of the trial. The goal is to determine if CBD can help reduce the negative effects associated with cannabis use and improve mental health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing cannabis use disorder, particularly those who use high-potency cannabis concentrates.
Not a fit: Patients who do not use cannabis or who are not experiencing issues related to cannabis use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new, accessible treatment option for individuals struggling with cannabis use disorder.
How similar studies have performed: Previous studies have shown promising results using synthetic CBD for cannabis use disorder, but this research is novel as it focuses on widely available hemp-derived CBD.
Where this research is happening
Boulder, UNITED STATES
- University of Colorado — Boulder, United States (Active)
Researchers
- Principal investigator: Bidwell, L. Cinnamon — University of Colorado
- Study coordinator: Bidwell, L. Cinnamon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.