Using hemp-derived cannabidiol to help people reduce cannabis use
Hemp-derived Cannabidiol for the treatment of cannabis use disorder in concentrate users: A double-blind placebo-controlled randomized trial
This study is looking at how well hemp-derived CBD can help people who are having trouble with cannabis use, especially those using strong cannabis products, by comparing two types of CBD—one with a little THC and one without—to see which one helps reduce withdrawal symptoms and cannabis use.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado NIH-funded |
| Lab location | 1 site (Boulder, UNITED STATES) |
| Project ID | NIH-10925377 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of hemp-derived cannabidiol (CBD) in treating cannabis use disorder, particularly among users of high-potency cannabis concentrates. The study will compare the effects of two forms of CBD—one with a small amount of THC and one without—on withdrawal symptoms and overall cannabis use. Participants will be randomly assigned to receive either CBD or a placebo, and their progress will be monitored over time to assess changes in cannabis consumption and related symptoms. This approach aims to provide a more accessible treatment option for individuals struggling with cannabis use disorder.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing cannabis use disorder, particularly those using high-potency concentrates.
Not a fit: Patients who do not use cannabis or who are not experiencing issues related to cannabis use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could offer a new, effective treatment for individuals seeking to reduce or quit cannabis use.
How similar studies have performed: Previous studies have shown promising results using synthetic CBD for cannabis use disorder, but this research is novel as it focuses on widely available hemp-derived CBD.
Where this research is happening
Boulder, UNITED STATES
- University of Colorado — Boulder, United States (Active)
Researchers
- Principal investigator: Bidwell, L. Cinnamon — University of Colorado
- Study coordinator: Bidwell, L. Cinnamon
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.