Using heart rate patterns to predict substance use in early adolescents

Respiratory Sinus Arrhythmia as a Predictor of Substance Use among Early Adolescents

['FUNDING_R01'] · RHODE ISLAND HOSPITAL · NIH-10866567

This study is looking at how changes in heart rate can help spot early signs of substance use risk in young teens by using a fun virtual reality task to see how they handle their emotions, which could help identify those who might need support before they start using drugs or alcohol.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorRHODE ISLAND HOSPITAL (nih funded)
Locations1 site (PROVIDENCE, UNITED STATES)
Trial IDNIH-10866567 on ClinicalTrials.gov

What this research studies

This research investigates how respiratory sinus arrhythmia (RSA), a measure of heart rate variability, can help identify early adolescents at risk for substance use. By utilizing a novel virtual reality task, researchers will assess emotion regulation patterns in adolescents, which are crucial for understanding their risk behaviors. The study aims to determine if RSA can serve as a reliable predictor of substance use, providing insights that do not rely on self-reported data. This approach could lead to early identification of at-risk youth, allowing for timely intervention.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who may be at risk for substance use due to emotional regulation challenges.

Not a fit: Patients who are outside the age range of 12 to 20 or those who do not exhibit any risk behaviors related to substance use may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved early identification and prevention strategies for substance use among adolescents.

How similar studies have performed: Previous research has shown promise in using physiological measures like RSA to predict emotional and behavioral outcomes, suggesting this approach may yield valuable insights.

Where this research is happening

PROVIDENCE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.