Using health information to improve care for tuberculosis and HIV in Africa
Official title: INnovative data Science to Impact the TB Epidemic - INSITE
Funded at University of Cape Town · NIH-11084565 · Data updated 2026-11-12
This project uses existing health records to better understand tuberculosis and HIV, especially in pregnant women, to improve care in South Africa.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Cape Town NIH-funded |
| Lab location | 1 site (Rondebosch, South Africa) |
| Project start | September 1, 2023 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $247,515 |
| NIH project number | 5U01TW012626-03 |
| Project ID | NIH-11084565 on NIH RePORTER |
Who could benefit from this research
✓Could help
This project focuses on data from patients in South Africa who have received care for tuberculosis and HIV, including pregnant women.
✕Less likely to help
Patients who do not have tuberculosis or HIV, or who are not located in South Africa, would not directly benefit from this specific data analysis.
What this research studies
This project aims to use large amounts of routine health data from clinics and hospitals in South Africa to gain new insights into tuberculosis (TB) and HIV. We want to understand how these diseases affect people, particularly pregnant women and their infants, and how different treatments interact. By analyzing this information, we hope to identify better ways to manage these conditions and ensure the safety of medications, especially for mothers and babies. This work will help healthcare providers make more informed decisions for patients in areas where TB and HIV are common.
Why it matters
Potential benefit: If successful, this work could lead to improved treatment strategies and safer medication use for people living with TB and HIV, especially pregnant women and their infants in South Africa.
How similar studies have gone: While using routine health data for epidemiological analysis is a recognized approach, applying it at scale in the specific context of TB and HIV in Africa, especially concerning maternal health and novel drug safety, presents unique challenges and opportunities.
Where this research is happening
-
University of Cape Town
Rondebosch, South Africa Active
Researchers
- Principal investigator: Kalk, Emma Kate — University of Cape Town
- Study coordinator: Kalk, Emma Kate
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.