Using health information to improve care for tuberculosis and HIV in Africa

INnovative data Science to Impact the TB Epidemic - INSITE

NIH-funded research University of Cape Town · NIH-11084565

This project uses existing health records to better understand tuberculosis and HIV, especially in pregnant women, to improve care in South Africa.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Cape Town NIH-funded
Lab location1 site (Rondebosch, South Africa)
Project IDNIH-11084565 on NIH RePORTER

What this research studies

This project aims to use large amounts of routine health data from clinics and hospitals in South Africa to gain new insights into tuberculosis (TB) and HIV. We want to understand how these diseases affect people, particularly pregnant women and their infants, and how different treatments interact. By analyzing this information, we hope to identify better ways to manage these conditions and ensure the safety of medications, especially for mothers and babies. This work will help healthcare providers make more informed decisions for patients in areas where TB and HIV are common.

Who could benefit from this research

Good fit: This project focuses on data from patients in South Africa who have received care for tuberculosis and HIV, including pregnant women.

Not a fit: Patients who do not have tuberculosis or HIV, or who are not located in South Africa, would not directly benefit from this specific data analysis.

Why it matters

Potential benefit: If successful, this work could lead to improved treatment strategies and safer medication use for people living with TB and HIV, especially pregnant women and their infants in South Africa.

How similar studies have performed: While using routine health data for epidemiological analysis is a recognized approach, applying it at scale in the specific context of TB and HIV in Africa, especially concerning maternal health and novel drug safety, presents unique challenges and opportunities.

Where this research is happening

Rondebosch, South Africa

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.