Using harmful molecules to create safe materials for healing
Official title: Biology the initiator: Harnessing Reactive Oxygen Species for Biocompatible Polymerization
Funded at University of Southern Mississippi · NIH-11055291 · Data updated 2026-11-12
This study is looking at how certain harmful molecules that increase after injuries, like heart attacks or strokes, can actually be used to create new materials that help heal damaged tissues, which could lead to better treatments for patients recovering from these conditions.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern Mississippi NIH-funded |
| Lab location | 1 site (Hattiesburg, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $199,800 |
| NIH project number | 5R21EB033533-03 |
| Project ID | NIH-11055291 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals recovering from heart attacks, strokes, or severe burn injuries.
✕Less likely to help
Patients with conditions unrelated to oxidative stress or those not experiencing significant tissue damage may not benefit from this research.
What this research studies
This research explores how reactive oxygen species (ROS), which are often harmful and increase after injuries like heart attacks or strokes, can be used positively to create biocompatible materials. By harnessing these molecules, the project aims to develop a method for polymerization that could lead to new materials that promote tissue regeneration at injury sites. The approach focuses on creating scaffolds that can adapt to the biological environment, potentially improving healing outcomes. Patients may benefit from innovative treatments that directly address tissue damage caused by oxidative stress.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that enhance healing and tissue regeneration after significant injuries.
How similar studies have gone: While the use of reactive oxygen species in therapeutic contexts is a novel approach, similar strategies in biomaterials have shown promise in preliminary studies.
Where this research is happening
-
University of Southern Mississippi
Hattiesburg, United States Active
Researchers
- Principal investigator: Clemons, Tristan — University of Southern Mississippi
- Study coordinator: Clemons, Tristan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.