Using guanfacine to help women with alcohol use disorder through telehealth
Official title: Guanfacine for women with AUD: A multisite study using a telehealth approach
Funded at Indiana University Indianapolis · NIH-10942227 · Data updated 2026-11-12
This study is looking at whether guanfacine can help women who struggle with drinking less alcohol, and it’s designed to be easy to join through telehealth, so you can participate from home even if you have other responsibilities or feel nervous about in-person visits.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project start | September 23, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $731,258 |
| NIH project number | 1R01AA031662-01 |
| Project ID | NIH-10942227 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women diagnosed with alcohol use disorder who are seeking treatment.
✕Less likely to help
Patients who do not have alcohol use disorder or those who are not women may not benefit from this research.
What this research studies
This research investigates the effectiveness of guanfacine, a medication, in reducing alcohol consumption among women with alcohol use disorder (AUD). It employs a telehealth approach to facilitate participation, making it easier for women who may face barriers such as caregiving responsibilities or stigma. The study will involve a 12-week clinical trial where participants will receive either guanfacine or a placebo, with the aim of assessing its impact on alcohol cravings and emotional regulation during stressful situations. The trial will recruit women from multiple sites, enhancing accessibility and compliance.
Why it matters
Potential benefit: If successful, this research could lead to a new treatment option specifically designed for women struggling with alcohol use disorder.
How similar studies have gone: Previous research has shown promise in using telehealth approaches for substance use treatment, indicating potential success for this novel application.
Where this research is happening
-
Indiana University Indianapolis
Indianapolis, United States Active
Researchers
- Principal investigator: Fox, Helen Cecilia — Indiana University Indianapolis
- Study coordinator: Fox, Helen Cecilia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.