Using guanfacine to help women with alcohol use disorder through telehealth

Guanfacine for women with AUD: A multisite study using a telehealth approach

NIH-funded research Indiana University Indianapolis · NIH-10942227

This study is looking at whether guanfacine can help women who struggle with drinking less alcohol, and it’s designed to be easy to join through telehealth, so you can participate from home even if you have other responsibilities or feel nervous about in-person visits.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis NIH-funded
Lab location1 site (Indianapolis, United States)
Project IDNIH-10942227 on NIH RePORTER

What this research studies

This research investigates the effectiveness of guanfacine, a medication, in reducing alcohol consumption among women with alcohol use disorder (AUD). It employs a telehealth approach to facilitate participation, making it easier for women who may face barriers such as caregiving responsibilities or stigma. The study will involve a 12-week clinical trial where participants will receive either guanfacine or a placebo, with the aim of assessing its impact on alcohol cravings and emotional regulation during stressful situations. The trial will recruit women from multiple sites, enhancing accessibility and compliance.

Who could benefit from this research

Good fit: Ideal candidates for this research are women diagnosed with alcohol use disorder who are seeking treatment.

Not a fit: Patients who do not have alcohol use disorder or those who are not women may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a new treatment option specifically designed for women struggling with alcohol use disorder.

How similar studies have performed: Previous research has shown promise in using telehealth approaches for substance use treatment, indicating potential success for this novel application.

Where this research is happening

Indianapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.