Using green tea extract to improve fertility in women with uterine fibroids

Reproductive Medicine Collaborative Consortium: a randomized placebo-controlled trial of EGCG to improve fertility in women with uterine fibroids- Application 4/4

NIH-funded research Yale University · NIH-10704544

This study is looking at how a green tea extract called EGCG might help women with uterine fibroids, which can affect their ability to get pregnant, by comparing it to a placebo to see if it can reduce fibroid size and improve fertility.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-10704544 on NIH RePORTER

What this research studies

This research investigates the effects of a green tea extract called EGCG on women suffering from uterine fibroids, which can hinder fertility. The study involves a randomized, double-blind, placebo-controlled trial where participants will receive either EGCG or a placebo to assess its impact on fibroid size and fertility outcomes. By focusing on a non-hormonal treatment option, the research aims to provide a safer alternative for women looking to conceive. Participants will be monitored for changes in fibroid volume and overall reproductive health.

Who could benefit from this research

Good fit: Ideal candidates for this research are women diagnosed with symptomatic uterine fibroids who are seeking to conceive.

Not a fit: Patients who do not have uterine fibroids or those who are not actively trying to conceive may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could offer a non-surgical, non-hormonal treatment option that improves fertility for women with uterine fibroids.

How similar studies have performed: Previous studies have shown promising results with EGCG in reducing fibroid size, indicating potential for success in this approach.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.