Using green tea extract to improve fertility in women with uterine fibroids
1/4 Reproductive Medicine Collaborative Consortium: a randomized placebo-controlled trial of EGCG to improve fertility in women with uterine fibroids
This study is looking at whether a green tea extract called EGCG can help women with uterine fibroids improve their chances of getting pregnant, and it’s designed for those who want a natural treatment option.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10694179 on NIH RePORTER |
What this research studies
This research investigates the effects of a green tea extract called EGCG on fertility in women suffering from uterine fibroids, which can hinder pregnancy. The study involves a randomized, double-blind, placebo-controlled trial where participants will receive either EGCG or a placebo to assess its impact on fibroid size and fertility outcomes. By focusing on a non-hormonal and non-surgical treatment option, the research aims to provide a safer alternative for women seeking to conceive despite the presence of fibroids.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with symptomatic uterine fibroids who are experiencing difficulty in achieving pregnancy.
Not a fit: Patients without uterine fibroids or those who are not seeking pregnancy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could offer a new, effective treatment option for women with fibroids who are trying to conceive.
How similar studies have performed: Previous studies have shown promising results with EGCG in reducing fibroid size, indicating potential for success in this approach.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Segars, James H. — Johns Hopkins University
- Study coordinator: Segars, James H.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.