Using green tea extract to help women with fibroids improve fertility

3/4, University of Illinois at Chicago Clinical Site- Reproductive Medicine Collaborative Consortium: A randomized placebo-controlled trial of EGCG to improve fertility in women with uterine fibroids

NIH-funded research University of Illinois at Chicago · NIH-10878669

This study is looking at whether a green tea extract called EGCG can help women with uterine fibroids reduce their fibroid size and improve their chances of getting pregnant, offering a natural treatment option for those who want to conceive.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project IDNIH-10878669 on NIH RePORTER

What this research studies

This research investigates the effects of a green tea extract called EGCG on women suffering from uterine fibroids, which can significantly impact fertility. The study involves a randomized, double-blind, placebo-controlled trial where participants will receive either EGCG or a placebo to assess its effectiveness in reducing fibroid size and improving chances of conception. By focusing on a non-hormonal treatment option, the research aims to provide a safer alternative for women who wish to conceive despite having fibroids. Participants will be monitored for changes in fibroid volume and overall fertility outcomes throughout the trial.

Who could benefit from this research

Good fit: Ideal candidates for this research are women of reproductive age who have been diagnosed with symptomatic uterine fibroids and are seeking to conceive.

Not a fit: Patients who do not have uterine fibroids or those who are not actively trying to conceive may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could offer a non-surgical and non-hormonal treatment option for women with fibroids, potentially improving their fertility.

How similar studies have performed: Previous studies have shown promising results with EGCG in reducing fibroid size, indicating that this approach may be effective.

Where this research is happening

Chicago, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.