Using grape seed extract to treat early stage lung cancer

Leucoselect Phytosome for Neoadjuvant Treatment of Early Stage Lung Cancer

['FUNDING_OTHER'] · VA SAN DIEGO HEALTHCARE SYSTEM · NIH-11043358

This study is looking at whether a special grape seed extract can help slow down early-stage lung cancer and improve treatment results for patients before their surgery.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorVA SAN DIEGO HEALTHCARE SYSTEM (nih funded)
Locations1 site (SAN DIEGO, UNITED STATES)
Trial IDNIH-11043358 on ClinicalTrials.gov

What this research studies

This research investigates the effects of a grape seed procyanidin extract, known as leucoselect phytosome, on early stage lung cancer. The study aims to determine if this extract can safely inhibit cancer growth and improve treatment outcomes by modulating various biological pathways associated with cancer progression. Patients will receive this treatment prior to surgery, and the research will monitor its impact on tumor markers and overall health. The approach is based on promising preclinical findings suggesting that this extract can positively influence cancer-related mechanisms.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with early stage lung cancer who are current or former smokers.

Not a fit: Patients with advanced lung cancer or those who are not smokers may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for patients with early stage lung cancer.

How similar studies have performed: Other research has shown promising results with similar approaches using grape seed extracts in cancer treatment, indicating potential for success in this study.

Where this research is happening

SAN DIEGO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: anti-cancer, Anti-Cancer Agents, anti-cancer drug

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.